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The trial involved 180 pregnant women undergoing monitoring for preterm preeclampsia at a large hospital in Cape Town, South Africa, between February 2018 and March 2020. Women were split into 2 arms: 90 received extended-release metformin and the other 90 received placebo. At the start of the trial, the women were 29 weeks pregnant on average and received either metformin or placebo until delivery.
COVID-19 prevention measures such as masking and social distancing have been loosened, which has left the public more vulnerable to influenza—especially since those same policies prevented people from building up natural immunity ahead of the coming cycle. Because so little of the influenza virus was in circulation last year, researchers also had less data to help determine which annual strains should be used in this season’s vaccines.
To further investigate the effectiveness of probiotics in reducing infections, researchers involved in the prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT) trial and the Canadian Critical Care Trials Group conducted a randomized placebo-controlled trial in 44 ICUs in Canada, the United States, and Saudi Arabia, enrolling adults predicted to require mechanical ventilation for at least 72 hours.
Part 1 (Pharmacy Today, February 2021) of this series on new FDA-approved therapeutic agents marketed in 2020 reviewed 5 new therapeutic agents: lasmiditan hemisuccinate (Reyvow–Lilly), ubrogepant (Ubrelvy–Allergan), rimegepant sulfate (Nurtec ODT–Biohaven), eptinezumab-jjmr (Vyepti–Lundbeck), and lemborexant (Dayvigo–Eisai).
Pharmacy Today provides news and information for pharmacy professionals to improve medication use and advance patient care. Each issue contains in-depth coverage of drugs and diseases, practice trends, and laws and regulations affecting the pharmacy profession.
Founded in 1852, APhA is the largest association of pharmacists in the U.S. with more than 62,000 practising pharmacists, pharmaceutical scientists, student pharmacists, and pharmacy technicians as members. More